TECNinox Bioreactor/Fermenter - Pharmaceutical/Chemical Machine

Seller's description

TECNinox Fermenter/Bioreactor suitable for: vaccine antigens | E. coli | yeast | recombinant proteins | microbial fermentation | pilot GMP production | scale-up | R&D

Originally Supplied Vaccine Production

General Description
Fermenter geometry 3:1
Fermenter head without sharp edges to improve cleaning, GMP gasket
Fermenter head with TC connections of various sizes (3/4, ½, 1), use them for additions, feeding, inoculation, etc.
Working volume for 36L bioreactor: 20L, minimum working volume 7.5L (positioning holder for probes)
Working volume for 74L bioreactor: 50L, dependent on position of last impeller
Operational pressure range: -0.01 to 3.00 bar g
Double mechanical seal
Motor position: overhead motor shaft, as close as possible to sparger and bottom
Impellers 3 Rushton / 3 Pitched Blade
Configurable motor speed 50-1500 rpm
Toroidal sparger with possibility of coupling and uncoupling
Exhaust gas condenser
Integrated CIP system
Exhaust gas management: double exhaust gas line after the outlet filter (the gas line must divide into two branches: one direct to the spent gas analysis system (airnova) and the other to the drain/waste)
Aeration 0 to 2. 5 VVM
Inlet air from above and from the sparger, with flowmeter
O2 inlet: 0 to 2.5 VVM, O2 inlet from above and from the sparger, with flowmeter
N2 inlet: 0 to 1 VVM, N2 inlet from above and from the sparger, with flowmeter
CO2 inlet 0 to 1 VVM, CO2 inlet from above and from the sparger, with flowmeter
Head pressure adjustment: automatic
Fixed speed pump with remote control
Variable speed pumps, two bottom valves
Bottom valve filter
Integrity test: integrated housing to perform in situ integrity test
Loading soil hole for manual loading
Fixed speed Peristaltic pumping, position adjacent to bioreactor pH, for control of acid/ base, CO2
Feeding base inlet via Sacova valve with ingold control

Vessel Sizes / Volumes
Total vessel sizes: 36L and 74L configurations:

Volumes & H/D Ratio

Total capacity : 36 L
Working capacity : 20 L
Diameter/Height: ratio 1/3

Total capacity : 74 L
Working capacity : 50 L
Diameter/Height : ratio 1/3

Ra Finish:
All product-contact surfaces polished to Ra ≤ 0.5 µm
Material: AISI 316L stainless steel (product contact parts)

Utilities needed to run:
Electrical requirements: 380v, 50Hz
Steam feed: 3 - 9 bar
Clean steam: 3 bar g
Purified water
Compressed air 8 bar g
Nitrogen: 8 bar
Refrigerated water: 9 - 12 deg C
Oxygen: 12 bar
CO2: 8 bar
Softened water
Drainage and discharge

This fermenter/bioreactor has two distinct agitation systems, one high shear and one low shear, with different impellor set ups. This allows for high turbidity and low turbidity applications, dependent on the application and organism being grown in the fermentation process.

The unit has the ability to run multiple types of organisms singularly from a minimum fermentation volume of 7.5L to a maximum of 75L however, the unit can run district volumes in between with the break point at 20L 30L giving the operator great flexibility.

The control software on this machine is TIA Portal which was introduced to the public in 2010 and according to Siemens it will be supported for 22 years and parts will be available for another 5 years after that. SIEMENS TIA is back words compatible. The machine is using a Siemens S7-300 PLC and Ilinox Asem MH215 HMI

Original OEM Documentation and Qualification Package Included

The system is supplied with its original TECNinox documentation package, retained from the original installation/project. The documentation is provided in the original OEM folders together with associated electronic media.

This represents a significant advantage for a pharmaceutical, vaccine or biotechnology purchaser, providing a strong technical basis for equipment review, recommissioning, qualification and future validation activities.

The documentation package includes the original equipment documentation and qualification records supplied with the system. A detailed documentation index can be provided to serious prospective purchasers on request.

Condition: AS NEW, UNUSED

Frequently Asked Questions (AI-Generated)

• What is the fermenter geometry of this TECNinox Fermenter/Bioreactor?

• This TECNinox Fermenter/Bioreactor has a fermenter geometry of 3:1.

• Does this equipment have a GMP gasket for easy cleaning?

• This equipment features a fermenter head without sharp edges to improve cleaning, equipped with GMP gaskets.

• What sizes of TC connections are included with this TECNinox Fermenter/Bioreactor?

• This TECNinox Fermenter/Bioreactor includes TC connections of various sizes (3/4, ½, 1) for additions, feeding, and inoculation.

• What is the working volume of this equipment?

• This equipment has a working volume of 20L for a 36L bioreactor and a minimum working volume of 7.5L.

• What is the maximum working volume of this TECNinox Fermenter/Bioreactor?

• This TECNinox Fermenter/Bioreactor has a working volume of 50L for a 74L bioreactor, dependent on the position of the last impeller.

• What is the pressure range for this equipment?

• This equipment operates within a pressure range of -0.01 to 3.00 bar g.

• Does this TECNinox Fermenter/Bioreactor have a double mechanical seal?

• This TECNinox Fermenter/Bioreactor is equipped with a double mechanical seal.

• Where is the motor shaft located on this equipment?

• This equipment features an overhead motor shaft positioned close to the sparger and bottom.

The following questions and answers are generated using artificial intelligence based on the product information available. They are provided for guidance only and may not reflect all specifications or conditions. Please contact us if you need precise or confirmed details.

Specifications

Category	Miscellaneous pharmaceutical / chemical machines
worked hours
hours under power
state	like new
At local norms	yes
status	visible but unplugged
Datasheet	Tecninox Fermenter/Bioreactor
Last availability date	03/11/2026
Product id	P230623106
Language	Language Резервоар за ферментатор/биореактор TECNinox Nádrž fermentoru/bioreaktoru TECNinox TECNinox Fermenter/Bioreactor Tank TECNinox Fermenter/Bioreaktortank TECNinox Fermenter/Bioreactor Tank TECNinox Bioreactor/Fermenter - Pharmaceutical/Chemical Machine Tanque fermentador/biorreactor TECNinox Réservoir de fermenteur/bioréacteur TECNinox TECNinox fermentor/bioreaktorski spremnik TECNinox fermentor/bioreaktor tartály Serbatoio fermentatore/bioreattore TECNinox TECNinox fermentatoriaus / bioreaktoriaus bakas TECNinox vergister/bioreactortank Zbiornik fermentora/bioreaktora TECNinox Tanque fermentador/biorreator TECNinox Rezervor de fermentare/bioreactor TECNinox Бак-ферментер/биореактор TECNinox TECNinok fermenter/bioreaktor rezervoar TECNinox Fermentor/Bioreactor Tank TECNinox Fermentör/Biyoreaktör Tankı

Automatic description (AI-Generated)

TECNinox Fermenter / Bioreactor — summary
This TECNinox fermenter/bioreactor is offered in 36 L and 74 L vessel configurations and is described as AS NEW, UNUSED. It is presented for applications including vaccine antigens, E. coli, yeast, recombinant proteins, microbial fermentation, pilot GMP production, scale-up and R&D.

Key vessel and mechanical features
- Geometry: height-to-diameter ratio 3:1
- Material: AISI 316L stainless steel for product-contact parts
- Surface finish: product-contact surfaces polished to Ra ≤ 0.5 µm
- Total capacities: 36 L and 74 L configurations
- Working capacities: 36 L model — 20 L (minimum working volume reported 7.5 L); 74 L model — 50 L (seller also indicates the unit can operate at volumes up to 75 L)
- Operational pressure range: -0.01 to 3.00 bar g
- Double mechanical seal; overhead motor shaft located close to sparger and bottom
- Agitation: three Rushton impellers and three pitched-blade impellers; the system includes two distinct agitation setups (high-shear and low-shear)
- Motor speed range: configurable 50–1500 rpm
- Toroidal sparger with coupling/uncoupling capability

Process, utilities and services
- Integrated CIP system and exhaust gas condenser
- Exhaust gas management: dual exhaust line after outlet filter (one branch directed to spent gas analysis system, the other to drain/waste)
- Aeration and gas inlets (each reported with flowmeter): air 0–2.5 VVM, O2 0–2.5 VVM, N2 0–1 VVM, CO2 0–1 VVM; inlet paths from above and from sparger
- Head pressure adjustment: automatic
- Pumps and valves: fixed-speed pump (remote control), variable-speed pumps, two bottom valves, bottom valve filter; fixed-speed peristaltic pump adjacent to pH for acid/base/CO2 control; feeding/base inlet via Sacova valve with ingold control
- Integrity test: integrated housing to perform in situ integrity testing
- Loading port for manual loading

Controls and documentation
- Control system: Siemens S7-300 PLC with TIA Portal software; HMI listed as Ilinox Asem MH215
- Original OEM documentation and qualification package supplied with the system (documentation retained from original installation/project; a detailed documentation index can be provided to serious prospective purchasers)

Utilities required (as reported)
- Electrical: 380 V, 50 Hz
- Steam feed 3–9 bar; clean steam 3 bar g
- Purified water, softened water, refrigerated water (9–12 °C)
- Compressed air 8 bar g; nitrogen 8 bar; oxygen 12 bar; CO2 8 bar
- Drainage and discharge

Condition and notes
- Condition reported as AS NEW, UNUSED
- Original OEM documentation and qualification package included

Please verify all details and suitability for your application during an on-site inspection; the description above reflects provided product information and original seller statements.

The following description has been generated using artificial intelligence based on the product information available. It is provided for guidance only and may not reflect all specifications or conditions. Please contact us if you need precise or confirmed details.