Used granulators 63


Zanchetta P2000 Pharmaceutical granulator

Year: 1990

granulator mixer Manufacturer : Zanchetta Model: P2000 Year: 1990 Refurbished in 2015


Diosna P250 Pharmaceutical granulator

Year:

Volume 250 L
Product type Solids
Speed (rpm) 3000 rpm
Motor Power 3 kW


FREWITT Mod. MG 633 - Oscillating Granulator used

Year:

DESCRIPTION: FREWITT Granulator Model MG 633 mounted on a mobile stainless steel frame. SECTORS OF USE: Pharmaceutical, chemical, cosmetics, food, dietary, medical devices, manufacturing. MAIN FEATURES: The machine is particularly suitable for sieving granulates obtained in a fluid bed, eliminating lumps, making the granulate uniform to the desired size and, above all, avoiding crushing the product creating dust. Wide range …

NIRO-FIELDER Mod. PMA 65 - High Speed Mixer Granulator used

Year:

DESCRIPTION: The PMA High Speed Granulator is a mixer suitable for high speed dispersion of dry powders, aqueous or solvent granulations and effervescent products. SECTORS OF USE: Pharmaceutical, chemical, cosmetics, food, dietary, medical devices, manufacturing. MAIN FEATURES: The overall concept of the New PMA-Compact stems from the common needs of consistent processing and ease of operation and cleaning. The mixing …


Frewitt MG-628 Pharmaceutical granulator

Year: 1991

Capacity 1000 kg/h
Product type Solids
Speed (rpm) 300 rpm
Motor Power 1 kW

Alexanderwerk WP 50 N75 Pharmaceutical granulator

Year: 1982

Capacity 40 kg/h
Product type Solids
Speed (rpm) 1380 rpm
Motor Power 2.2 kW

Diosna P-250 Pharmaceutical granulator

Year: 1985

Volume 250 L
Product type Solids
Speed (rpm) 180 rpm
Motor Power 6.5 kW

Frewitt MG633 Pharmaceutical granulator

Year:

oscillating granulator Frewitt MG633, VA version, on metal frame, without operating instructions




Sagitta GR 450 / S2 Pharmaceutical granulator

Year: 2001

Capacity 2800 kg/h
Product type Solids
Speed (rpm) 1440 rpm
Motor Power 4 kW


Gea Niro Fielder Nica M6 extrusion and spheronization

Year: 1993

Manufacturer: GEA Model: Niro Fielder Nica M6 extrusion and spheronization

Aeromatic Gea PMA 1800 Pharmaceutical granulator

Year:

Capacity 825 kg/h
Speed (rpm) 3000 rpm
Motor Power 11 kW
Volume 1800 L
Product type Solids

High Shear Mixer Granulator

Year: 2022

Capacity 40 kg/h
Speed (rpm) 1440 rpm
Motor Power 3.72856 kW
Volume 100 L
Product type Solids


Pharmaceutical Granulator Machine

Granulation is a significant phase in the chemical, pharmaceutical and cosmetic process. It refers to the process of collecting powder particles together through either bond agents or compression. One of the main purposes of granulation is to prevent the segregation of the constituents of powder mix. Many powders, because of their small size, irregular shape or surface characteristics, are cohesive and do not flow well. Granules produced from such a cohesive system will be larger and more isodiametric, both factors contributing to improved flow properties. In pharmaceutical processes, granulation can also be used to bond different agents together to create a chemical reaction.

Types of Pharmaceutical Granulators

The pharmaceutical industry employs two types of granulation techniques which are wet granulation and dry granulation. Wet granulation process acquires granulation liquid to be added into powder to bond the components together. The binder or adhesive is incorporated in the form of a solution in a suitable liquid. The liquid should be non-toxic and water is preferably used for this purpose. During dry granulation process granules are formed without any additional liquid because the final product might be sensitive to moisture.

Pharmaceutical Wet Granulators

Depending on the type of influence under which liquid is added into powder, there are three main types of wet granulators. High shear granulator where liquid is added under influence of the impeller. Twin screw generator where liquid is added under influence of screws. Or fluidized bed granulator with liquid added by means of an airflow. Agitation of the particles along with the added liquid produces bonding between the primary powder particles to produce wet granules. To finalize the process of granulation, liquid is evaporated to leave the granules with particles holding together with the adhesive binder. The dried mixture may need to be milled or granulated to get the final pellet size. Complexity of wet granulation process depends on the characteristics of the powders and the desired final result. The whole process starts when liquid is added into powder, the powder gets wet and a thin film is formed between powder particles. The more liquid is added into powder, the more substantial the film gets which provides stronger adhesion between particles when liquid is finally evaporated.

Types of Wet Granulators

  • Planetary mixer can be used for wet mixing (planetary mixers are used for dry mixing as well). If dry components are required to be mixed together, the prior use of specific dry mixers (depending on the nature of the powder) will be needed. They will then be added into the mixing vessel.
  • High shear granulator. This type of granulator usually comprises mixing bowl with a bottom entry impeller and a side mounted chopper. Impeller is needed for mixing ingredients and chopper for further granulation. All dry ingredients are agitated into the mixing bowl and then run the chopper blade in order to achieve granulation. The binding agent is added during the blending process through a spraying nozzle.
  • Fluidized bed granulator. Powder granules are fluidized using streams of air. In this type of granulator, the liquid properties of the powder allow a homogeneous granulation. The liquid may be heated before it is sprayed into the bed of powder.

Pharmaceutical Dry Granulators

In dry granulation process granules are formed without addition of any liquid solution. Dry granulation is performed using a slugging tool or a tablet press machine. The end point of granulation can be determined by several principles, for example when the desired particle size is reached.

Oscillating Granulator

Oscillating granulator can be used for both dry and wet granulation process. It plays a significant role in the process of granulation as the final product (tablet) quality depends on the virtue of the granules used for its compression. This type of pharmaceutical granulator is extensively used to mill or granulate solid chunk of material into powder or granules. Unique oscillatory rotor action ensures high outputs and a high-quality product with minimum flaws.

Area of Use

Granulators are mainly used in pharmaceutical industry, as well as chemical and cosmetic industries.  Granulators are used for production of tablets, pellets and powder.

Main Manufacturers

Glatt granulators as well as granulators by Bohle and GEA are the most popular manufacturers in the category. Among main manufacturers of granulators also belong brands like Aeromatic, Frewitt and Koruma.

Related Subcategories

  • Tablet presses - rotary / rotary compacting presses
  • Tablet presses - single-punch / eccentric / single station press
  • Tablet coating machines