Лиофилизатори - сушилни чрез замразяване
Lyofilizace - stroje a zařízení
Lyofilisatorer - frysetørrere
Gefriertrocknern
Λυοφιλοποιητές - λυοφιλοποιητές
Lyophilizers - freeze dryers
Liofilizadores
Lyophilisateurs
Liofilizatori - sušači smrzavanjem
Liofilizálók - fagyasztva szárítók
Liofilizzatori
Liofilizatoriai – džiovinimo šaldikliai
Lyofilisatoren - vriesdrogers
Liofilizatory
Liofilizadores - liofilizadores
Liofilizatoare - liofilizatoare
Лиофилизаторы
Liofilizatori - sušare za zamrzavanje
Lyofilisatorer - frystorkar
Liyofilizatörler - Dondurarak kurutucular
At Exapro, we connect buyers with a wide range of high-quality used lyophilizers and used freeze dryers, essential for preserving and stabilizing sensitive biological and chemical products. Whether you need a laboratory unit, a pilot-scale model, or a full production system, our marketplace features listings from leading brands such as VirTis, SP Scientific, Telstar, and GEA Group. Choosing a used freeze dryer allows you to achieve the same reliability and precision as new equipment while keeping costs under control.
With prices typically ranging from €20,000 to €150,000, these machines are ideal for pharmaceuticals, biotechnology, and food processing industries where product integrity and extended shelf life are critical. Buying second-hand doesn’t mean compromising on performance — many used lyophilizers deliver the same efficiency, consistency, and compliance as new models.
Explore our range of used lyophilizers and freeze dryers today!
Showing 1 - 20 out of 34
Netherlands
2007
| Chamber volume | 340 L |
|---|---|
| Nbr of trays | 6 |
| Tray surface | 0.74 m² |
|---|
Netherlands
2016
| Tray surface | 0.48 m² |
|---|---|
| Minimal T° | 55 °C |
| Freeze trap capacity | 22 L |
|---|
Netherlands
2016
| Tray surface | 0.48 m² |
|---|---|
| Minimal T° | 55 °C |
| Freeze trap capacity | 22 L |
|---|
Italy
2000
| Chamber volume | -6 L |
|---|---|
| Freeze trap capacity | 90 L |
| Nbr of trays | 6 |
| Tray surface | 1 m² |
|---|---|
| Minimal T° | 60 °C |
France
2009
| Chamber volume | 683 L |
|---|---|
| Minimal T° | -65 °C |
| Tray surface | 1.02 m² |
|---|---|
| Nbr of trays | 4 |
Spain
2017
Bulgaria
2022
Poland
1980
| Chamber volume | 20 L |
|---|---|
| Freeze trap capacity | 5 L |
| Nbr of trays | 2 |
| Tray surface | 0.2 m² |
|---|---|
| Minimal T° | 40 °C |
Greece
2019
| Tray surface | 0.25 m² |
|---|---|
| Minimal T° | 53.3 °C |
| Freeze trap capacity | 8 L |
|---|
| Chamber volume | 645 L |
|---|---|
| Freeze trap capacity | 2.2 L |
| Nbr of trays | 6 |
| Tray surface | 0.36 m² |
|---|---|
| Minimal T° | -80 °C |
Italy
1997
Germany
2026
Netherlands
1998
| Tray surface | 0.6 m² |
|---|---|
| Nbr of trays | 4 |
| Freeze trap capacity | 20 L |
|---|
Netherlands
2006
| Tray surface | 0.95 m² |
|---|
| Nbr of trays | 6 |
|---|
Italy
2001
Switzerland
1991
| Chamber volume | 590 L |
|---|
Lyophilization ensures product stability, potency, and long shelf life by removing moisture through sublimation without compromising structure. On Exapro, buyers can find high-quality used lyophilizers suitable for pharmaceutical, biotech, and food industries — from laboratory R&D to full GMP production. Purchasing pre-owned equipment allows you to access reliable performance immediately, without the delays and high costs of new machines.
Each used freeze dryer on Exapro is listed with key specifications such as shelf area, condenser capacity, and vacuum system details. Many include maintenance records, manuals, and validation files, helping buyers meet regulatory expectations with reduced commissioning risks. This transparency simplifies your purchasing decision while ensuring compliance readiness.
Exapro’s team provides personalized assistance at every step — from comparing listings to coordinating inspections, transport, and installation. We help you select machines suited to your batch sizes, product types, and facility constraints so that your investment delivers maximum productivity and reliability.
Freeze dryers are crucial for preserving sensitive products such as vaccines, biologics, and premium food ingredients. Investing in a used lyophilizer through Exapro combines technical reliability with substantial savings, providing a cost-effective path to scale up your production capacity.
Used lyophilizers typically cost 60–70% less than new models while maintaining top-tier performance. This reduced capital expenditure accelerates ROI and leaves room for complementary investments such as utilities, validation tools, or automation upgrades.
Freeze drying preserves the molecular structure and stability of sensitive materials, ensuring long-term product quality. Many used units have operated under GMP environments and include maintenance logs, reducing qualification time and operational risks.
Exapro offers a full range — from laboratory-scale lyophilizers for research to industrial production systems meeting FDA and EMA requirements. These systems are built for repeatability, process control, and audit readiness.
Choosing pre-owned freeze dryers supports circular economy principles by extending equipment lifespan and minimizing waste. You also benefit from shorter lead times and reduced environmental impact compared to manufacturing new machinery.
When evaluating a used lyophilizer, it’s essential to assess technical parameters that influence cycle efficiency, temperature control, and vacuum performance. These features directly impact product quality and regulatory compliance.
Determine the chamber volume and shelf area based on your batch size. Consider vial configurations, tray dimensions, and loading ergonomics to ensure even heat transfer and reproducible results.
Low shelf and condenser temperatures are critical for drying heat-sensitive formulations. Adequate condenser capacity prevents vapor overload and improves drying speed, ensuring consistent cycle times.
A tight vacuum system minimizes leaks and improves energy efficiency. Verify pump type (oil or dry), door sealing, and valve condition to ensure stable low-pressure operation throughout the cycle.
Modern systems feature PLC/HMI interfaces with recipe management, alarms, and monitoring tools. Verify support for 21 CFR Part 11, audit trails, and secure data storage for compliant manufacturing.
Integrated Clean-in-Place (CIP) and Sterilize-in-Place (SIP) systems simplify maintenance and improve aseptic assurance. Chambers and shelves made of stainless steel with polished finishes guarantee hygiene and durability.
Depending on your needs, select between lab-scale units for R&D, pilot systems for scale-up, and production-scale lyophilizers for commercial manufacturing. Industrial food-grade dryers handle large volumes for continuous operations.
Exapro lists lyophilizers from leading manufacturers recognized for engineering quality and regulatory compliance. These brands deliver durable, validated solutions for laboratories and production plants worldwide:
Lyophilization technology supports diverse sectors that require moisture removal and product preservation under strict process control. Here are the most common applications:
Used lyophilizers on Exapro generally range from €20,000 to €150,000. Several key variables influence pricing, from technical capacity to compliance features and documentation availability.
Selecting the right freeze dryer involves balancing technical needs, compliance requirements, and facility capabilities. Follow these steps to secure a system aligned with your production goals:
Clarify target batch sizes, vial types, and throughput goals. Whether for R&D or full-scale manufacturing, ensure shelf area and condenser capacity meet your product’s thermal sensitivity and expected cycle duration.
Confirm that the unit follows GMP guidelines and supports FDA/EMA standards. Availability of validation protocols, user access controls, and audit trails will streamline qualification.
Review shelf arrangement, loading mechanisms, and tray formats to ensure even temperature distribution and scalability. Flexible design allows adaptation to multiple product types.
Always verify vacuum integrity, compressor performance, and system cleanliness. Request test cycles or inspection videos to evaluate the unit’s operational state before purchase.
Check your site’s power, water, cooling, and ventilation compatibility. Proper planning prevents downtime and ensures safe, efficient commissioning.
Exapro specialists can help you compare listings, arrange on-site inspections, and manage transport and installation logistics to ensure a smooth acquisition process.
Browse our latest listings of used lyophilizers and freeze dryers and connect with verified global sellers. Exapro offers technical guidance, inspection assistance, and full logistics coordination — making it easier than ever to upgrade your production line with confidence.
Turkey
Hungary
EN
- Languages
English (GB)