| Manufacturer | MilliporeSigma |
|---|---|
| Model | Ultrafiltration / Diafiltration TFF SKID |
| Year | 2020 |
| Location | USA
|
MilliporeSigma Cogent CPS Size B — tangential ultrafiltration/diafiltration (TFF) system designed for process scale. Standalone configuration (own reservoir to be transported). The system is supplied with a comprehensive set of components from leading manufacturers and extensive documentation for integration and validation. Product reservoir/container is not included in the kit.
Key features and equipment:
- Cogent CPS Size B platform (MilliporeSigma) with Pellicon™ cassette holder (Pellicon PEH1150HHPT4, 1.5" TC, 316L housing, EPDM seals) and hydraulic compression system for the cassettes (hydraulic control, operating pressure up to 0–138 barg as specified in documentation).
- Pumps: Quattroflow feed pump (four-plunger diaphragm pump, sanitary 2" TC), Watson‑Marlow peristaltic transfer pump.
- Measurement and analytics: Endress+Hauser Promass F 100 Coriolis flowmeters (DN40 and DN25), Optek UV/VIS and conductivity sensors with converter.
- Valves and sanitary fittings: GEMÜ diaphragm control valves, sanitary ball valves, Swagelok check valves, NEUMO/MaxPure 316L sanitary fittings, and sanitary piping (Sandvik 316L).
- CIP/SIP system and sanitary features; NovAseptic® valves and mixer for aseptic mixing, diamond-coated mixer bearings for long life.
- Control: Allen‑Bradley CompactLogix PLC, Siemens HMI, PowerFlex frequency drives, CCP/orm (CCP®) interface for recipes, audit trails, and batch report generation (GAMP and FDA 21CFR Part 11 compatibilities indicated in documentation).
- Electrical equipment and panels by Saginaw Controls, UPS integration option to maintain control data.
Documentation and extended package:
- Full ETOP package with 1649 pages; recirculation package totaling 5269 pages; original P&IDs, software instructions, installation procedures, and electrical schematics (approx. 75 pages). Documentation includes protocols, calibration certificates, and QC protocols facilitating integration and qualification.
Options and functionalities (included/offered): low-volume bypass, inlet collection manifold for peristaltic pump, mass flow meter for feed, conductivity and UV filtrate monitoring, Pellicon holder with control box (manual or hydraulic closure), mass flow meter for filtrate, NovaSeptum® sampling for retentate and filtrate, UPS connection.
Materials:
- All product-contact surfaces: 316L stainless steel, electro-polished to ≤20 Ra (EP); EPDM seals, USP Class VI where indicated.
Notes:
- Product reservoir/container not included. Described reservoir and bypass kits are buyer-applied integration items.
- Specifications and listings use original documentation; serial numbers and details of previous operators are excluded from this description. Upon request, I can prepare a condensed list of key models for verification or extract parts critical to your integration and validation strategy.
The following description has been generated using artificial intelligence based on the product information available. It is provided for guidance only and may not reflect all specifications or conditions. Please contact us if you need precise or confirmed details.
MilliporeSigma Cogent Lab Ultrafiltration / Diafiltration TFF System
A complete MilliporeSigma Cogent CPS Size B Tangential Flow Filtration skid — built new for Novavax/AGC, never field-deployed in long-term production, . Self-contained TFF process skid: bring your own tank. Tier-1 components throughout (Quattroflow, Watson-Marlow, Endress+Hauser, Optek-Danulat, Allen-Bradley, MilliporeSigma, GEMÜ, LABOM), full 1,649-page turnover package, all cal certs and MTRs in hand.
Exceptionally well maintained and well documented Novavax surplus. Complete, fully documented, GMP-grade fluid processing skid (minus tankski), with high-end pump, mixer, valve network, instrumentation, and full engineering + QA traceabilit
Placed out of service 22 October 2022 per AGC Biologics .
Decommissioning included full certification per GMP standards.
Includes complete original comprehensive turnover package (5,269 total pages)
Also includes original General Arrangement drawing and complete Electrical Wiring Diagram package (75 pages) from system integrator Holland Applied Technologies.
The tank skid shown in the drawings is not included. The EWD and turnover docs contain exhaustive, precise, detailed documentation for your engineer to integrate your own tank skid and/or bypasses to your precise process needs.
Included Configuration
(See markup in photos)
Option 2: Low volume bypass
This option is used to minimize the recirculation volume, avoiding introducing air in the line, which could damage proteins or create foam. The retentate recycle will start to be used as soon as the level in the tank will go under the retentate return pipe. The option is mainly required when a customer tank is connected to our skid with flexible hoses or if maximum concentration is needed. Note: Tank Outlet Level Switch is required when using the tank recycle to allow efficient final concentration step.
Option 3A: Peristaltic transfer pump with inlet manifold
The transfer of product / buffers into the feed tank from any other tank. The manifold allows connecting several inlets at the same time, avoiding several connections/disconnections.
Option 5: Feed mass flowmeter
Option 7: Filtrate conductivity
Measurement of a wide range of products (WFI, buffer solutions, protein solutions) or post CIP flushing monitoring.
Option 11: Filtrate UV
Measurement of a wide range of products (WFI, buffer solutions, protein solutions) or post CIP flushing monitoring.
Option 15: Pellicon® Holder with control box
The Pellicon® Process-scale Holder is uniquely designed to reduce the time required to install and remove TFF devices for production scale while keeping the flow path unchanged. The holder can be configured either with manual or hydraulic closure. Hydraulic closure can be done with a hand pump or with an automated hydraulic box which allows local or distant control.
Benefits:
• Compact footprint
• TFF devices can be installed/removed quickly
• Easy to vent and fully drain, maximizes product recovery
• Easy retrofit from manual to hydraulic closure
• Flow path unchanged, minimizes future re-qualification and validation effort in new process application
Option 16: Filtrate mass flowmeter
Filtrate flow and total volume monitoring in diafiltration mode
Option 18: Retentate and filtrate NovaSeptum® sampling port
In process sterile sampling of product.
NovAseptum® sampling consumables have to be ordered separately.
Option 25B: Connection to customer UPS
External power supply to prevent data lost in case of power supply failure . All the power components like pumps, mixer, etc... remain connected to the main power supply during 15min, the time for operator to safely turn off the system
EMBEDDED NOVASEPTIC® VALVES AND MIXER:
• Comply with cGMP Design Qualification criteria for aseptic processing.
• NovAseptic® connector ensures no dead legs and maximum product recovery with zero hold up volume
• Comply with the most stringent cleanability and sterilizability requirements.
• Mixer is clean running and is suitable for general mixing, heat transfer and shear sensitive applications.
• Reduced bioburden.
• Lower cost of maintenance.
• Mixer new diamond coated bearings ensures long life and optimum performance.
• Ability to mix the “last drop”, ensures complete product recovery.
PROCESS CONTROL:
The Cogent® Process Scale Tangential Flow Filtration System is easilly controlled via the Common Control Platform® (CCP®) a powerful, intuitive, graphical software interface that provides real-time monitoring and total in-depth control of your TFF process. Using industrially robust PCs, PLCs and SCADA® technology it meets the most stringent standards for connectivity, reliability and ease of use. Benefits :
• Create process operations using the recipe editor, monitor or control the process in the home screen and create reports for the batch using the configurable report generator.
• Developed under GAMP guidelines and FDA 21CFR Part 11 compliance-ready, including audit trails and electronic signatures for verification.
• Sensors combination can be adapted to process requirements allowing the maximum confidence in process monitoring.
• Utilities to connect all of your separation unit operations to a central network or DCS (e.g. Delta V).
• Used on multiple unit operations CCP provides one familiar interface to simplify software management and reduce learning curves.
Built for vaccine manufacturing
1. OEM pedigree. This is a Millipore-built CPS — MilliporeSigma's flagship process-scale TFF platform.
2. Built for vaccine manufacturing. Original end user was Novavax (), built through AGC Biologics as integrator. Phase III / commercial-grade vaccine pedigree
3. The Pellicon TFF holder. MilliporeSigma PEH1150HHPT4 — Millipore's premium hydraulic-compression Pellicon cassette holder, 1.5" TC, 316L body, EPDM gaskets. The full hydraulic intensifier system is included (Interface Devices H030/30-00PM-1GA, NoShok 0–3000 PSI gauge, GEMÜ ePos 1435 intelligent positioner driving cassette compression at 0–138 barg).
4. Bring-your-own-tank flexibility.
5. Complete documentation package. 1,649-page ETOP — mill test reports, calibration certificates (LABOM, Optek, Mettler Toledo, Endress+Hauser), QC release certs, software install procedures, electrical drawings, P&IDs, PLC program. Buyers in pharma will pay a premium just for the docs because re-qualifying without them is brutal.
6. Fully automated, ready to validate. Allen-Bradley PLC + Siemens HMI, two PowerFlex 70 VFDs for both pumps, full instrumentation suite.
Hard-spec talking points
Process pumps:
Feed pump (P-001): Quattroflow QF10KACU 4-piston piston-diaphragm, 2" TC, ~10,000 L/h, 6 barg max. S/N 816665. The gold standard for shear-sensitive biologics.
Transfer pump (P-401): Watson-Marlow 701FB peristaltic, paired with NORD SK 90SP/4 motor (1.5 HP / 1.1 kW, IE3, IP55 TEFC, S/N 34597744)
TFF & hydraulic compression system:
MilliporeSigma Pellicon hydraulic-compression cassette holder PEH1150HHPT4 (1.5" TC, 316L, EPDM gaskets) — the centerpiece
Interface Devices H030/30-00PM-1GA hydraulic intensifier (air → 3000 PSI), S/N 20-0338-HY, install date 6/30/20
NoShok P12-5674 hydraulic pressure gauge, 0–3000 PSI
GEMÜ ePos 1435 intelligent valve positioner (PY-001), S/N 88092764
LABOM hydraulic pressure transmitter (PIT-501)
MilliporeSigma HB-501 hydraulic box (HA87110), 0–138 barg operating
MilliporeSigma CIP/SIP Plate (PEH0PTCIP1)
Coriolis flow measurement (2 units — major value):
FT-001: Endress+Hauser Promass F 100, 8F1B40-4L08/0, DN40 (1.5"), 4–20 mA = 0–330 lb/min, HART, S/N R700DC16000
FT-101: Endress+Hauser Promass F 100, 8F1B25-5NJ9/0, DN25 (1.0")
Process pressure instrumentation (LABOM throughout):
PT-002, PT-003, PT-101 — LABOM CC6010 family sanitary pressure transmitters with DL3230 diaphragm seals
PIT-001, PIT-401 — LABOM CS2110 family
Optek-Danulat analytical:
AE-101: F20 UV/VIS absorption sensor body, 1" TC, 8mm flow cell, S/N 108986 — body 0120-2911-33, MS3 8M5 sapphire optics, AF45-VB module, 10m cable
AE-102: F40 inductive conductivity sensor, 1" TC, S/N 107905 — body 0120-2918-33, ACF60-35-22 sensor, 10m cable, integral RTD (TE-101)
AIT-101: Optek C8480 dual-channel UV+conductivity+temp transmitter, 24V AC/DC, S/N 108489
Process valves & sanitary fittings:
GEMÜ 650 40D59401723T1 SF5 sanitary diaphragm control valve
4× PBM SIHL sanitary manual ball valves (HV-203/204/206/207, 0.75" and 1" BW)
PBM XV-205 actuated ball valve
Swagelok SS-CHS8-1/3 check valve (CV-602), Swagelok HV-501
Kunkle/NASVI 911BDCM01-AJE sanitary safety pressure relief valve (PRV-202)
BS&B 1.5" GCR-SM rupture disc (BD-201), 3 bar burst @ 50°C, includes 2 spares
LJ Star sanitary sight glass + light
Kodiak Controls KC302D15860 mechanical pressure gauges
TECMAQ Tri-Clamp adapters (104968, 55358, 71028228)
~50+ NEUMO MaxPure 316L electropolished sanitary fittings (elbows, tees, ferrules, reducers, 0.5"–2.0")
Sandvik 21.3 mm OD seamless 316L tubing
Watson-Marlow Pumpsil 913.A254.PFT silicone flex hose (×2)
HAT silicone flex hose set
Pneumatics:
SMC PCV-601/602 filter+regulator combos
SMC HV-601/602 manual pneumatic shut-off + lockout (VHS40-N04B-Z)
SMC ISE40A-N01-Y-PK-X531 digital pressure switch (PISL-601)
SMC XV-601 solenoid
Controls — enclosures:
Saginaw Controls SCE-60EL3616SSLP main enclosure, 60×36×16, 304SS Type 4X IP66
Saginaw Controls SCE-60P36 back panel
Saginaw Controls SCE-24EL2008SS6LP sub-enclosure, 24×20×8, 304SS Type 4X
Siemens SIMATIC HMI door touchscreen
Allen-Bradley 194R 30A fused 480V door disconnect
Allen-Bradley 194E 16A 120V UPS load switch
3× Mersen 480DB1 25A 480V distribution modules
Phoenix Contact QUINT 24VDC 20A power supply
Controls — PLC & I/O:
Allen-Bradley CompactLogix 1769-L33ER PLC
2× Allen-Bradley PowerFlex 70 VFDs (matched-set, sequential serials):
SIC-001 Feed pump drive: 20AD8P0C3AYNAEC0, 5 HP / 4 kW, S/N 80797724
SIC-401 Transfer pump drive: 20AD3P4C3AYNAEC0, 2 HP / 1.5 kW, S/N 80797722
Both with 20-COMM-E EtherNet/IP adapters
Murr Elektronik Cube20 BN-E EtherNet/IP head + 6× Cube20 A14 4-ch analog input modules
SICK FLEXI Soft safety controller (CPU0 + 2× XTIO)
Allen-Bradley safety relay
Materials/finish:
Every wetted surface 316L SS, electropolished to ≤20 Ra Max + EP
Some lines down to <0.4 µm Ra (Optek bodies)
USP Class VI EPDM elastomers throughout
HOW THIS ITEM WAS TESTED
This unit was decommissioned in 2022 by Novavax after only two years in use. It is believed to be fully functional.
Please note that this description may have been translated or optimized with artificial intelligence (AI) automatically. The information of this classified ad are only indicative. We recommend to check the details with the seller before a purchase.
| Client type | Machinery dealer |
| Active since | 2026 |
| Offers online | 1 |
| Last activity | July 31, 2026 |
MilliporeSigma Cogent Lab Ultrafiltration / Diafiltration TFF System
A complete MilliporeSigma Cogent CPS Size B Tangential Flow Filtration skid — built new for Novavax/AGC, never field-deployed in long-term production, . Self-contained TFF process skid: bring your own tank. Tier-1 components throughout (Quattroflow, Watson-Marlow, Endress+Hauser, Optek-Danulat, Allen-Bradley, MilliporeSigma, GEMÜ, LABOM), full 1,649-page turnover package, all cal certs and MTRs in hand.
Exceptionally well maintained and well documented Novavax surplus. Complete, fully documented, GMP-grade fluid processing skid (minus tankski), with high-end pump, mixer, valve network, instrumentation, and full engineering + QA traceabilit
Placed out of service 22 October 2022 per AGC Biologics .
Decommissioning included full certification per GMP standards.
Includes complete original comprehensive turnover package (5,269 total pages)
Also includes original General Arrangement drawing and complete Electrical Wiring Diagram package (75 pages) from system integrator Holland Applied Technologies.
The tank skid shown in the drawings is not included. The EWD and turnover docs contain exhaustive, precise, detailed documentation for your engineer to integrate your own tank skid and/or bypasses to your precise process needs.
Included Configuration
(See markup in photos)
Option 2: Low volume bypass
This option is used to minimize the recirculation volume, avoiding introducing air in the line, which could damage proteins or create foam. The retentate recycle will start to be used as soon as the level in the tank will go under the retentate return pipe. The option is mainly required when a customer tank is connected to our skid with flexible hoses or if maximum concentration is needed. Note: Tank Outlet Level Switch is required when using the tank recycle to allow efficient final concentration step.
Option 3A: Peristaltic transfer pump with inlet manifold
The transfer of product / buffers into the feed tank from any other tank. The manifold allows connecting several inlets at the same time, avoiding several connections/disconnections.
Option 5: Feed mass flowmeter
Option 7: Filtrate conductivity
Measurement of a wide range of products (WFI, buffer solutions, protein solutions) or post CIP flushing monitoring.
Option 11: Filtrate UV
Measurement of a wide range of products (WFI, buffer solutions, protein solutions) or post CIP flushing monitoring.
Option 15: Pellicon® Holder with control box
The Pellicon® Process-scale Holder is uniquely designed to reduce the time required to install and remove TFF devices for production scale while keeping the flow path unchanged. The holder can be configured either with manual or hydraulic closure. Hydraulic closure can be done with a hand pump or with an automated hydraulic box which allows local or distant control.
Benefits:
• Compact footprint
• TFF devices can be installed/removed quickly
• Easy to vent and fully drain, maximizes product recovery
• Easy retrofit from manual to hydraulic closure
• Flow path unchanged, minimizes future re-qualification and validation effort in new process application
Option 16: Filtrate mass flowmeter
Filtrate flow and total volume monitoring in diafiltration mode
Option 18: Retentate and filtrate NovaSeptum® sampling port
In process sterile sampling of product.
NovAseptum® sampling consumables have to be ordered separately.
Option 25B: Connection to customer UPS
External power supply to prevent data lost in case of power supply failure . All the power components like pumps, mixer, etc... remain connected to the main power supply during 15min, the time for operator to safely turn off the system
EMBEDDED NOVASEPTIC® VALVES AND MIXER:
• Comply with cGMP Design Qualification criteria for aseptic processing.
• NovAseptic® connector ensures no dead legs and maximum product recovery with zero hold up volume
• Comply with the most stringent cleanability and sterilizability requirements.
• Mixer is clean running and is suitable for general mixing, heat transfer and shear sensitive applications.
• Reduced bioburden.
• Lower cost of maintenance.
• Mixer new diamond coated bearings ensures long life and optimum performance.
• Ability to mix the “last drop”, ensures complete product recovery.
PROCESS CONTROL:
The Cogent® Process Scale Tangential Flow Filtration System is easilly controlled via the Common Control Platform® (CCP®) a powerful, intuitive, graphical software interface that provides real-time monitoring and total in-depth control of your TFF process. Using industrially robust PCs, PLCs and SCADA® technology it meets the most stringent standards for connectivity, reliability and ease of use. Benefits :
• Create process operations using the recipe editor, monitor or control the process in the home screen and create reports for the batch using the configurable report generator.
• Developed under GAMP guidelines and FDA 21CFR Part 11 compliance-ready, including audit trails and electronic signatures for verification.
• Sensors combination can be adapted to process requirements allowing the maximum confidence in process monitoring.
• Utilities to connect all of your separation unit operations to a central network or DCS (e.g. Delta V).
• Used on multiple unit operations CCP provides one familiar interface to simplify software management and reduce learning curves.
Built for vaccine manufacturing
1. OEM pedigree. This is a Millipore-built CPS — MilliporeSigma's flagship process-scale TFF platform.
2. Built for vaccine manufacturing. Original end user was Novavax (), built through AGC Biologics as integrator. Phase III / commercial-grade vaccine pedigree
3. The Pellicon TFF holder. MilliporeSigma PEH1150HHPT4 — Millipore's premium hydraulic-compression Pellicon cassette holder, 1.5" TC, 316L body, EPDM gaskets. The full hydraulic intensifier system is included (Interface Devices H030/30-00PM-1GA, NoShok 0–3000 PSI gauge, GEMÜ ePos 1435 intelligent positioner driving cassette compression at 0–138 barg).
4. Bring-your-own-tank flexibility.
5. Complete documentation package. 1,649-page ETOP — mill test reports, calibration certificates (LABOM, Optek, Mettler Toledo, Endress+Hauser), QC release certs, software install procedures, electrical drawings, P&IDs, PLC program. Buyers in pharma will pay a premium just for the docs because re-qualifying without them is brutal.
6. Fully automated, ready to validate. Allen-Bradley PLC + Siemens HMI, two PowerFlex 70 VFDs for both pumps, full instrumentation suite.
Hard-spec talking points
Process pumps:
Feed pump (P-001): Quattroflow QF10KACU 4-piston piston-diaphragm, 2" TC, ~10,000 L/h, 6 barg max. S/N 816665. The gold standard for shear-sensitive biologics.
Transfer pump (P-401): Watson-Marlow 701FB peristaltic, paired with NORD SK 90SP/4 motor (1.5 HP / 1.1 kW, IE3, IP55 TEFC, S/N 34597744)
TFF & hydraulic compression system:
MilliporeSigma Pellicon hydraulic-compression cassette holder PEH1150HHPT4 (1.5" TC, 316L, EPDM gaskets) — the centerpiece
Interface Devices H030/30-00PM-1GA hydraulic intensifier (air → 3000 PSI), S/N 20-0338-HY, install date 6/30/20
NoShok P12-5674 hydraulic pressure gauge, 0–3000 PSI
GEMÜ ePos 1435 intelligent valve positioner (PY-001), S/N 88092764
LABOM hydraulic pressure transmitter (PIT-501)
MilliporeSigma HB-501 hydraulic box (HA87110), 0–138 barg operating
MilliporeSigma CIP/SIP Plate (PEH0PTCIP1)
Coriolis flow measurement (2 units — major value):
FT-001: Endress+Hauser Promass F 100, 8F1B40-4L08/0, DN40 (1.5"), 4–20 mA = 0–330 lb/min, HART, S/N R700DC16000
FT-101: Endress+Hauser Promass F 100, 8F1B25-5NJ9/0, DN25 (1.0")
Process pressure instrumentation (LABOM throughout):
PT-002, PT-003, PT-101 — LABOM CC6010 family sanitary pressure transmitters with DL3230 diaphragm seals
PIT-001, PIT-401 — LABOM CS2110 family
Optek-Danulat analytical:
AE-101: F20 UV/VIS absorption sensor body, 1" TC, 8mm flow cell, S/N 108986 — body 0120-2911-33, MS3 8M5 sapphire optics, AF45-VB module, 10m cable
AE-102: F40 inductive conductivity sensor, 1" TC, S/N 107905 — body 0120-2918-33, ACF60-35-22 sensor, 10m cable, integral RTD (TE-101)
AIT-101: Optek C8480 dual-channel UV+conductivity+temp transmitter, 24V AC/DC, S/N 108489
Process valves & sanitary fittings:
GEMÜ 650 40D59401723T1 SF5 sanitary diaphragm control valve
4× PBM SIHL sanitary manual ball valves (HV-203/204/206/207, 0.75" and 1" BW)
PBM XV-205 actuated ball valve
Swagelok SS-CHS8-1/3 check valve (CV-602), Swagelok HV-501
Kunkle/NASVI 911BDCM01-AJE sanitary safety pressure relief valve (PRV-202)
BS&B 1.5" GCR-SM rupture disc (BD-201), 3 bar burst @ 50°C, includes 2 spares
LJ Star sanitary sight glass + light
Kodiak Controls KC302D15860 mechanical pressure gauges
TECMAQ Tri-Clamp adapters (104968, 55358, 71028228)
~50+ NEUMO MaxPure 316L electropolished sanitary fittings (elbows, tees, ferrules, reducers, 0.5"–2.0")
Sandvik 21.3 mm OD seamless 316L tubing
Watson-Marlow Pumpsil 913.A254.PFT silicone flex hose (×2)
HAT silicone flex hose set
Pneumatics:
SMC PCV-601/602 filter+regulator combos
SMC HV-601/602 manual pneumatic shut-off + lockout (VHS40-N04B-Z)
SMC ISE40A-N01-Y-PK-X531 digital pressure switch (PISL-601)
SMC XV-601 solenoid
Controls — enclosures:
Saginaw Controls SCE-60EL3616SSLP main enclosure, 60×36×16, 304SS Type 4X IP66
Saginaw Controls SCE-60P36 back panel
Saginaw Controls SCE-24EL2008SS6LP sub-enclosure, 24×20×8, 304SS Type 4X
Siemens SIMATIC HMI door touchscreen
Allen-Bradley 194R 30A fused 480V door disconnect
Allen-Bradley 194E 16A 120V UPS load switch
3× Mersen 480DB1 25A 480V distribution modules
Phoenix Contact QUINT 24VDC 20A power supply
Controls — PLC & I/O:
Allen-Bradley CompactLogix 1769-L33ER PLC
2× Allen-Bradley PowerFlex 70 VFDs (matched-set, sequential serials):
SIC-001 Feed pump drive: 20AD8P0C3AYNAEC0, 5 HP / 4 kW, S/N 80797724
SIC-401 Transfer pump drive: 20AD3P4C3AYNAEC0, 2 HP / 1.5 kW, S/N 80797722
Both with 20-COMM-E EtherNet/IP adapters
Murr Elektronik Cube20 BN-E EtherNet/IP head + 6× Cube20 A14 4-ch analog input modules
SICK FLEXI Soft safety controller (CPU0 + 2× XTIO)
Allen-Bradley safety relay
Materials/finish:
Every wetted surface 316L SS, electropolished to ≤20 Ra Max + EP
Some lines down to <0.4 µm Ra (Optek bodies)
USP Class VI EPDM elastomers throughout
HOW THIS ITEM WAS TESTED
This unit was decommissioned in 2022 by Novavax after only two years in use. It is believed to be fully functional.
Please note that this description may have been translated or optimized with artificial intelligence (AI) automatically. The information of this classified ad are only indicative. We recommend to check the details with the seller before a purchase.
MilliporeSigma Cogent CPS Size B — tangential ultrafiltration/diafiltration (TFF) system designed for process scale. Standalone configuration (own reservoir to be transported). The system is supplied with a comprehensive set of components from leading manufacturers and extensive documentation for integration and validation. Product reservoir/container is not included in the kit.
Key features and equipment:
- Cogent CPS Size B platform (MilliporeSigma) with Pellicon™ cassette holder (Pellicon PEH1150HHPT4, 1.5" TC, 316L housing, EPDM seals) and hydraulic compression system for the cassettes (hydraulic control, operating pressure up to 0–138 barg as specified in documentation).
- Pumps: Quattroflow feed pump (four-plunger diaphragm pump, sanitary 2" TC), Watson‑Marlow peristaltic transfer pump.
- Measurement and analytics: Endress+Hauser Promass F 100 Coriolis flowmeters (DN40 and DN25), Optek UV/VIS and conductivity sensors with converter.
- Valves and sanitary fittings: GEMÜ diaphragm control valves, sanitary ball valves, Swagelok check valves, NEUMO/MaxPure 316L sanitary fittings, and sanitary piping (Sandvik 316L).
- CIP/SIP system and sanitary features; NovAseptic® valves and mixer for aseptic mixing, diamond-coated mixer bearings for long life.
- Control: Allen‑Bradley CompactLogix PLC, Siemens HMI, PowerFlex frequency drives, CCP/orm (CCP®) interface for recipes, audit trails, and batch report generation (GAMP and FDA 21CFR Part 11 compatibilities indicated in documentation).
- Electrical equipment and panels by Saginaw Controls, UPS integration option to maintain control data.
Documentation and extended package:
- Full ETOP package with 1649 pages; recirculation package totaling 5269 pages; original P&IDs, software instructions, installation procedures, and electrical schematics (approx. 75 pages). Documentation includes protocols, calibration certificates, and QC protocols facilitating integration and qualification.
Options and functionalities (included/offered): low-volume bypass, inlet collection manifold for peristaltic pump, mass flow meter for feed, conductivity and UV filtrate monitoring, Pellicon holder with control box (manual or hydraulic closure), mass flow meter for filtrate, NovaSeptum® sampling for retentate and filtrate, UPS connection.
Materials:
- All product-contact surfaces: 316L stainless steel, electro-polished to ≤20 Ra (EP); EPDM seals, USP Class VI where indicated.
Notes:
- Product reservoir/container not included. Described reservoir and bypass kits are buyer-applied integration items.
- Specifications and listings use original documentation; serial numbers and details of previous operators are excluded from this description. Upon request, I can prepare a condensed list of key models for verification or extract parts critical to your integration and validation strategy.
The following description has been generated using artificial intelligence based on the product information available. It is provided for guidance only and may not reflect all specifications or conditions. Please contact us if you need precise or confirmed details.
| Client type | Machinery dealer |
| Active since | 2026 |
| Offers online | 1 |
| Last activity | July 31, 2026 |
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Система TFF для ультрафильтрации и диафильтрации Cogent Lab от MilliporeSigma
Sistem za ultrafiltraciju/dijafiltraciju TFF MiliporSigma Kodžent Lab
MilliporeSigma Cogent Lab TFF-system för ultrafiltrering/diafiltrering
MilliporeSigma Cogent Lab Ultrafiltrasyon / Diafiltrasyon TFF Sistemi
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